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Optimod – An automated approach for constructing and optimizing initial models for single-particle electron microscopy
Single-particle cryo-electron microscopy is now well established as a technique for the structural characterization of large macromolecules and macromolecular complexes. The raw data is very noisy and consists of two-dimensional projections, from which the 3D biological object must be reconstructed....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885246/ https://ncbi.nlm.nih.gov/pubmed/24161732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.10.009 |
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