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Optimod – An automated approach for constructing and optimizing initial models for single-particle electron microscopy

Single-particle cryo-electron microscopy is now well established as a technique for the structural characterization of large macromolecules and macromolecular complexes. The raw data is very noisy and consists of two-dimensional projections, from which the 3D biological object must be reconstructed....

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Bibliografski detalji
Glavni autori: Lyumkis, Dmitry, Vinterbo, Staal, Potter, Clinton S., Carragher, Bridget
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885246/
https://ncbi.nlm.nih.gov/pubmed/24161732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.10.009
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