MYH9 and APOL1 are both associated with sickle cell disease nephropathy

BACKGROUND: Renal failure occurs in 5–18% of sickle cell disease (SCD) patients and is associated with early mortality. At risk SCD patients cannot be identified prior to the appearance of proteinuria and the pathobiology is not well understood. The MYH9 and APOL1 genes have been associated with ris...

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Autori principali: Ashley-Koch, Allison E., Okocha, Emmanuel C., Garrett, Melanie E., Soldano, Karen, De Castro, Laura M., Jonassaint, Jude C., Orringer, Eugene P., Eckman, James R., Telen, Marilyn J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3885232/
https://ncbi.nlm.nih.gov/pubmed/21910715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08832.x
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