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Differential roles for the Co(2+)/Ni(2+) transporting ATPases, CtpD and CtpJ, in Mycobacterium tuberculosis virulence
The genome of Mycobacterium tuberculosis encodes two paralogous P(1B4)-ATPases, CtpD (Rv1469) and CtpJ (Rv3743). Both proteins showed ATPase activation by Co(2+) and Ni(2+), and both appear to be required for metal efflux from the cell. However, using a combination of biochemical and genetic studies...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3885230/ https://ncbi.nlm.nih.gov/pubmed/24255990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12454 |
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