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Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells

DNA mismatch repair (MMR) is involved in processing DNA damage following treatment with ionising radiation (IR) and various classes of chemotherapy drugs including iododeoxyuridine (IUdR), a known radiosensitiser. In this study, the authors have developed asynchronous probabilistic cell cycle models...

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書誌詳細
主要な著者: Gurkan‐Cavusoglu, Evren, Schupp, Jane E., Kinsella, Timothy J., Loparo, Kenneth A.
フォーマット: Artigo
言語:Inglês
出版事項: The Institution of Engineering and Technology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884822/
https://ncbi.nlm.nih.gov/pubmed/23919954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb.2012.0050
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