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Developing an in silico model of the modulation of base excision repair using methoxyamine for more targeted cancer therapeutics
Base excision repair (BER) is a major DNA repair pathway involved in the processing of exogenous non‐bulky base damages from certain classes of cancer chemotherapy drugs as well as ionising radiation (IR). Methoxyamine (MX) is a small molecule chemical inhibitor of BER that is shown to enhance chemo...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Institution of Engineering and Technology
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3884826/ https://ncbi.nlm.nih.gov/pubmed/23847811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb.2011.0045 |
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