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Quantitative analysis of the effects of iododeoxyuridine and ionising radiation treatment on the cell cycle dynamics of DNA mismatch repair deficient human colorectal cancer cells

DNA mismatch repair (MMR) is involved in processing DNA damage following treatment with ionising radiation (IR) and various classes of chemotherapy drugs including iododeoxyuridine (IUdR), a known radiosensitiser. In this study, the authors have developed asynchronous probabilistic cell cycle models...

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Autori principali: Gurkan‐Cavusoglu, Evren, Schupp, Jane E., Kinsella, Timothy J., Loparo, Kenneth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Institution of Engineering and Technology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884822/
https://ncbi.nlm.nih.gov/pubmed/23919954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1049/iet-syb.2012.0050
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