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Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization

Spinal muscular atrophy is a neuromuscular disease resulting from mutations in the SMN1 gene, which encodes the survival motor neuron (SMN) protein. SMN is part of a large complex that is essential for the biogenesis of spliceosomal small nuclear RNPs. SMN also colocalizes with mRNAs in granules tha...

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Détails bibliographiques
Auteurs principaux: Rage, Florence, Boulisfane, Nawal, Rihan, Khalil, Neel, Henry, Gostan, Thierry, Bertrand, Edouard, Bordonné, Rémy, Soret, Johann
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884661/
https://ncbi.nlm.nih.gov/pubmed/24152552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.040204.113
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