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Specific splicing defects in S. pombe carrying a degron allele of the Survival of Motor Neuron gene
Spinal muscular atrophy results from deletions or mutations in the survival of motor neuron (SMN1) gene. The SMN protein has an essential role in the biogenesis of spliceosomal snRNPs, but the link between a defect in this process and specific splicing inhibition of pre-mRNAs has not been establishe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885929/ https://ncbi.nlm.nih.gov/pubmed/20400941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.70 |
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