Transgenic expression of PML/RARalpha impairs myelopoiesis.

The translocation found in acute promyelocytic leukemia rearranges the promyelocytic leukemia gene (PML) on chromosome 15 with the retinoic acid receptor alpha (RARalpha) on chromosome 17. This yields a fusion transcript, PML/RARalpha, a transcription factor with reported dominant negative functions...

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Detaylı Bibliyografya
Yayımlandı:	Proc Natl Acad Sci U S A
Asıl Yazarlar:	Early, E, Moore, M A, Kakizuka, A, Nason-Burchenal, K, Martin, P, Evans, R M, Dmitrovsky, E
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	National Academy of Sciences 1996
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7900
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Transgenic expression of PML/RARalpha impairs myelopoiesis.

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