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Structural Determinants of Drug Partitioning in Surrogates of Phosphatidylcholine Bilayer Strata

The knowledge of drug concentrations in bilayer headgroups, core, and at the interface between them is a prerequisite for quantitative modeling of drug interactions with many membrane-bound transporters, metabolizing enzymes and receptors, which have the binding sites located in the bilayer. This kn...

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Detalhes bibliográficos
Main Authors: Lukacova, Viera, Natesan, Senthil, Peng, Ming, Tandlich, Roman, Wang, Zhanbin, Lynch, Sandra, Subramaniam, Rajesh, Balaz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884577/
https://ncbi.nlm.nih.gov/pubmed/23964749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400204y
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