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Partitioning of Organic Compounds in Phases Imitating the Headgroup and Core Regions of Phospholipids Bilayers

Solvation free energies of drugs, peptides, and other small molecules in the core and headgroup regions of phospholipid bilayers determine their conformations, accumulation, and transport properties. The transfer free energy includes the energy terms for the formation of a cavity for the solute, the...

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Main Authors: Lukacova, Viera, Peng, Ming, Tandlich, Roman, Hinderliter, Anne, Balaz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896065/
https://ncbi.nlm.nih.gov/pubmed/16460120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la052187j
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