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Drug-Membrane Interactions Studied in Phospholipid Monolayers Adsorbed on Non-porous Alkylated Microspheres

Characterization of interactions with phospholipids is an integral part of the in vitro profiling of drug candidates because of the roles the interactions play in tissue accumulation and passive diffusion. Currently used test systems may inadequately emulate the bilayer core solvation properties (im...

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Autors principals: LUKACOVA, VIERA, PENG, MING, FANUCCI, GAIL, TANDLICH, ROMAN, HINDERLITER, ANNE, MAITY, BIKASH, MANIVANNAN, ETHIRAJAN, COOK, GREGORY R., BALAZ, STEFAN
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896050/
https://ncbi.nlm.nih.gov/pubmed/17218665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057106297063
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