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Structural Determinants of Drug Partitioning in n-Hexadecane/Water System

Surrogate phases have been widely used as correlates for modeling transport and partitioning of drugs in biological systems, taking advantage of chemical similarity between the surrogate and the phospholipid bilayer as the elementary unit of biological phases, which is responsible for most of transp...

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Detalhes bibliográficos
Main Authors: Natesan, Senthil, Wang, Zhanbin, Lukacova, Viera, Peng, Ming, Subramaniam, Rajesh, Lynch, Sandra, Balaz, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733081/
https://ncbi.nlm.nih.gov/pubmed/23641957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci400112k
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