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Interaction of Benzodiazepines with Central Nervous Glycine Receptors: Possible Mechanism of Action

Interaction of 21 benzodiazepines with the glycine receptor in the brainstem and spinal cord of rat have been evaluated in terms of their displacement of [(3)H]strychinine binding. The rank order of potency of the 21 drugs in displacing specific [(3)H]strychinine binding correlates (p < 0.005) wi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Young, Anne B., Zukin, Stephen R., Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388428/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4152296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2246
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