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Interaction of Benzodiazepines with Central Nervous Glycine Receptors: Possible Mechanism of Action

Interaction of 21 benzodiazepines with the glycine receptor in the brainstem and spinal cord of rat have been evaluated in terms of their displacement of [(3)H]strychinine binding. The rank order of potency of the 21 drugs in displacing specific [(3)H]strychinine binding correlates (p < 0.005) wi...

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Autores principales: Young, Anne B., Zukin, Stephen R., Snyder, Solomon H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1974
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC388428/
https://ncbi.nlm.nih.gov/pubmed/4152296
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