Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development.

Intrathymic T-cell development requires temporally regulated rearrangement and expression of T-cell receptor (TCR) genes. To assess the role of the TCR beta gene transcriptional enhancer (Ebeta) in this process, mouse strains in which Ebeta is deleted were generated using homologous recombination te...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bouvier, G, Watrin, F, Naspetti, M, Verthuy, C, Naquet, P, Ferrier, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7877
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