Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development.

Intrathymic T-cell development requires temporally regulated rearrangement and expression of T-cell receptor (TCR) genes. To assess the role of the TCR beta gene transcriptional enhancer (Ebeta) in this process, mouse strains in which Ebeta is deleted were generated using homologous recombination te...

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Bibliografiska uppgifter
Huvudupphovsmän: Bouvier, G, Watrin, F, Naspetti, M, Verthuy, C, Naquet, P, Ferrier, P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC38842/
https://ncbi.nlm.nih.gov/pubmed/8755570
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