Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development.

Intrathymic T-cell development requires temporally regulated rearrangement and expression of T-cell receptor (TCR) genes. To assess the role of the TCR beta gene transcriptional enhancer (Ebeta) in this process, mouse strains in which Ebeta is deleted were generated using homologous recombination te...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bouvier, G, Watrin, F, Naspetti, M, Verthuy, C, Naquet, P, Ferrier, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755570/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.7877
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