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Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.

We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryonic stem cell line. A cloned fragment of the beta 2-microglobulin gene with the coding sequence disrupted by the insertion of the neomycin-resistance gene was used to transfect the embryonic stem cells....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Koller, B H, Smithies, O
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1989
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC298404/
https://ncbi.nlm.nih.gov/pubmed/2682666
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