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Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.

We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryonic stem cell line. A cloned fragment of the beta 2-microglobulin gene with the coding sequence disrupted by the insertion of the neomycin-resistance gene was used to transfect the embryonic stem cells....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Koller, B H, Smithies, O
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1989
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8932
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