Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.
We have inactivated, by gene targeting, the endogenous beta 2-microglobulin gene in a mouse embryonic stem cell line. A cloned fragment of the beta 2-microglobulin gene with the coding sequence disrupted by the insertion of the neomycin-resistance gene was used to transfect the embryonic stem cells....
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Proc Natl Acad Sci U S A |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
1989
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2682666/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.22.8932 |
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