Pharmacological blockade of either cannabinoid CB(1) or CB(2) receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of cell proliferation in the hippocampus of adult male rat

Addiction to major drugs of abuse, such as cocaine, has recently been linked to alterations in adult neurogenesis in the hippocampus. The endogenous cannabinoid system modulates this proliferative response as demonstrated by the finding that pharmacological activation/blockade of cannabinoid CB(1) a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blanco-Calvo, Eduardo, Rivera, Patricia, Arrabal, Sergio, Vargas, Antonio, Pavón, Francisco Javier, Serrano, Antonia, Castilla-Ortega, Estela, Galeano, Pablo, Rubio, Leticia, Suárez, Juan, Rodriguez de Fonseca, Fernando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884150/
https://ncbi.nlm.nih.gov/pubmed/24409127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnint.2013.00106
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