Pharmacological blockade of either cannabinoid CB(1) or CB(2) receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of cell proliferation in the hippocampus of adult male rat

Addiction to major drugs of abuse, such as cocaine, has recently been linked to alterations in adult neurogenesis in the hippocampus. The endogenous cannabinoid system modulates this proliferative response as demonstrated by the finding that pharmacological activation/blockade of cannabinoid CB(1) a...

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Detalhes bibliográficos
Main Authors: Blanco-Calvo, Eduardo, Rivera, Patricia, Arrabal, Sergio, Vargas, Antonio, Pavón, Francisco Javier, Serrano, Antonia, Castilla-Ortega, Estela, Galeano, Pablo, Rubio, Leticia, Suárez, Juan, Rodriguez de Fonseca, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884150/
https://ncbi.nlm.nih.gov/pubmed/24409127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnint.2013.00106
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