Pharmacological Blockade of Cannabinoid CB(1) Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle

Cannabinoid CB(1) receptors peripherally modulate energy metabolism. Here, we investigated the role of CB(1) receptors in the expression of glucose/pyruvate/tricarboxylic acid (TCA) metabolism in rat abdominal muscle. Dihydrolipoamide dehydrogenase (DLD), a flavoprotein component (E3) of α-ketoacid...

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Bibliographic Details
Published in:PLoS One
Main Authors: Arrabal, Sergio, Lucena, Miguel Angel, Canduela, Miren Josune, Ramos-Uriarte, Almudena, Rivera, Patricia, Serrano, Antonia, Pavón, Francisco Javier, Decara, Juan, Vargas, Antonio, Baixeras, Elena, Martín-Rufián, Mercedes, Márquez, Javier, Fernández-Llébrez, Pedro, De Roos, Baukje, Grandes, Pedro, Rodríguez de Fonseca, Fernando, Suárez, Juan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4682857/
https://ncbi.nlm.nih.gov/pubmed/26671069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145244
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