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Factor VIIa binding to endothelial cell protein C receptor: Differences between mouse and human systems
Recent in vitro studies have shown that the zymogen and activated form of FVII bind to endothelial cell protein C receptor (EPCR). At present, there is no evidence that FVIIa binds to EPCR on vascular endothelium in vivo in the presence of circulating protein C, a primary ligand for EPCR. The presen...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3883592/ https://ncbi.nlm.nih.gov/pubmed/22370814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH11-09-0672 |
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