RAS Promotes Tumorigenesis through Genomic Instability Induced by imbalanced expression of Aurora-A and BRCA2 urian

The oncogene RAS is known to induce genomic instability, leading to cancer development; the underlying mechanism, however, remains poorly understood. To better understand how RAS functions, we measured the activity of the functionally related genes Aurora-A and BRCA2 in ovarian cancer cell lines and...

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Hlavní autoři: Yang, Gong, Mercado-Uribe, Imelda, Multani, Asha S., Sen, Subrata, Shih, Ie-Ming, Wong, Kwong-Kwok, Gershenson, David M, Liu, Jinsong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883442/
https://ncbi.nlm.nih.gov/pubmed/23319376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28032
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