The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

Epithelial–stromal interactions play a critical role in tumor initiation and progression; cancer-associated stroma, but not normal stroma, is known to be tumor-promoting. However, the molecular signal used by epithelial cancer cells to reprogram normal stroma to a tumorigenic stroma is not known. He...

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Detalhes bibliográficos
Main Authors: Yang, Gong, Rosen, Daniel G., Zhang, Zhihong, Bast, Robert C., Mills, Gordon B., Colacino, Justin A., Mercado-Uribe, Imelda, Liu, Jinsong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637606/
https://ncbi.nlm.nih.gov/pubmed/17060621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605752103
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