Prevention of Malignant Change in Mammalian Cells During Prolonged Culture In Vitro
Mixed cultures of epithelial cells and fibroblasts, derived from primary cultures of the skin of embryo rats, grown always in rubber-stoppered T-60 flasks, first yielded a transplantable tumor from the 52nd passage, at the end of 13 months of frequently repeated subculture. A group of subcultures, d...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388323/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4525292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.1780 |
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