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Prevention of Malignant Change in Mammalian Cells During Prolonged Culture In Vitro

Mixed cultures of epithelial cells and fibroblasts, derived from primary cultures of the skin of embryo rats, grown always in rubber-stoppered T-60 flasks, first yielded a transplantable tumor from the 52nd passage, at the end of 13 months of frequently repeated subculture. A group of subcultures, d...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Goldblatt, Harry, Friedman, Libby
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1974
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388323/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4525292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.5.1780
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