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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

Summary: Methionine addiction, found in all types of cancer investigated, is because of the overuse of methionine by cancer cells for excess transmethylation reactions. In the present study, we compared the histone H3 lysine-methylation status and degree of malignancy between methionine-addicted can...

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Bibliographic Details
Main Authors: Jun Yamamoto, Sachiko Inubushi, Qinghong Han, Yoshihiko Tashiro, Norihiko Sugisawa, Kazuyuki Hamada, Yusuke Aoki, Kentaro Miyake, Ryusei Matsuyama, Michael Bouvet, Steven G. Clarke, Itaru Endo, Robert M. Hoffman
Format: Artigo
Language:Inglês
Published: Elsevier 2022-04-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222004321
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