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The retinoic acid receptor-α modulators ATRA and Ro415253 reciprocally regulate human IL-5+ Th2 cell proliferation and cytokine expression

BACKGROUND: Th2 cytokine responses are enhanced by all trans retinoic acid (ATRA), the bioavailable form of vitamin A. Retinoic acid receptor alpha (RARα) is the high affinity receptor for ATRA that mediates these pro-Th2 effects. We have previously characterized two major human Th2 subpopulations:...

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Bibliografiset tiedot
Päätekijät: Wansley, Daniel L, Yin, Yuzhi, Prussin, Calman
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882882/
https://ncbi.nlm.nih.gov/pubmed/24314292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-11-4
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