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Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders

BACKGROUND: Anti-IgE therapy inhibits mast cell and basophil activation, blocks IgE binding to both FcεRI and CD23 and down regulates FcεRI expression by antigen (Ag) presenting cells (APCs). In addition to its classical role in immediate hypersensitivity, IgE has been shown in vitro to facilitate A...

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Main Authors: Foster, Barbara, Foroughi, Shabnam, Yin, Yuzhi, Prussin, Calman
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098204/
https://ncbi.nlm.nih.gov/pubmed/21527026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-9-7
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