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Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders

BACKGROUND: Anti-IgE therapy inhibits mast cell and basophil activation, blocks IgE binding to both FcεRI and CD23 and down regulates FcεRI expression by antigen (Ag) presenting cells (APCs). In addition to its classical role in immediate hypersensitivity, IgE has been shown in vitro to facilitate A...

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Detalhes bibliográficos
Main Authors: Foster, Barbara, Foroughi, Shabnam, Yin, Yuzhi, Prussin, Calman
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098204/
https://ncbi.nlm.nih.gov/pubmed/21527026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-9-7
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