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In vivo electrophysiology of nigral and thalamic neurons in alpha-synuclein-overexpressing mice highlights differences from toxin-based models of parkinsonism

Numerous studies have suggested that alpha-synuclein plays a prominent role in both familial and idiopathic Parkinson's disease (PD). Mice in which human alpha-synuclein is overexpressed (ASO) display progressive motor deficits and many nonmotor features of PD. However, it is unclear what in vi...

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Detalhes bibliográficos
Main Authors: Lobb, C. J., Zaheer, A. K., Smith, Y., Jaeger, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882812/
https://ncbi.nlm.nih.gov/pubmed/24068758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00441.2013
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