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Membrane Tethered Delta Activates Notch and Reveals a Role for Spatio-Mechanical Regulation of the Signaling Pathway
Short-range Notch receptor signaling is necessary for coordinating developmental activities in metazoa. To investigate this juxtacrine pathway, we mimic receptor-ligand binding within the cell-cell junction by engaging Notch1-eGFP expressing cells to a supported lipid membrane displaying Delta-like...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882513/ https://ncbi.nlm.nih.gov/pubmed/24359737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.012 |
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