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VEGF and Delta-Notch: interacting signalling pathways in tumour angiogenesis

Tumour angiogenesis has become an important target for antitumour therapy, with most current therapies aimed at blocking the VEGF pathway. However, not all tumours are responsive to VEGF blockers, and some tumours that are responsive initially may become resistant during the course of treatment, thu...

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Detalhes bibliográficos
Main Authors: Thurston, G, Kitajewski, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570514/
https://ncbi.nlm.nih.gov/pubmed/18827808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604484
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