An Explicit Formulation Approach for the Analysis of Calcium Binding to EF-Hand Proteins Using Isothermal Titration Calorimetry

We present an improved and extended version of a recently proposed mathematical approach for modeling isotherms of ligand-to-macromolecule binding from isothermal titration calorimetry. Our approach uses ordinary differential equations, solved implicitly and numerically as initial value problems, to...

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Autores principales: Keeler, Camille, Poon, Gregory, Kuo, Ivana Y., Ehrlich, Barbara E., Hodsdon, Michael E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2013
Materias:
Systems Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882476/
https://ncbi.nlm.nih.gov/pubmed/24359756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.11.017
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