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Characterization of the 1(st )and 2(nd )EF-hands of NADPH oxidase 5 by fluorescence, isothermal titration calorimetry, and circular dichroism
BACKGROUND: Superoxide generated by non-phagocytic NADPH oxidases (NOXs) is of growing importance for physiology and pathobiology. The calcium binding domain (CaBD) of NOX5 contains four EF-hands, each binding one calcium ion. To better understand the metal binding properties of the 1(st )and 2(nd )...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386892/ https://ncbi.nlm.nih.gov/pubmed/22490336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-6-29 |
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