HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol-induced parenchymal cell injury

Hepatic stellate cells (HSC) and liver endothelial cells (LEC) migrate to sites of injury and perpetuate alcohol-induced liver injury. High-mobility group box 1 (HMGB1) is a protein released from the nucleus of injured cells that has been implicated as a proinflammatory mediator. We hypothesized tha...

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Autori principali: Seo, Yeon S., Kwon, Jung H., Yaqoob, Usman, Yang, Liu, De Assuncao, Thiago M., Simonetto, Douglas A., Verma, Vikas K., Shah, Vijay H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2013
Soggetti:
Inflammation/Immunity/Mediators
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882432/
https://ncbi.nlm.nih.gov/pubmed/24091596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00151.2013
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