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The Three-State Model: A Minimal Allosteric Description of Homotropic and Heterotropic Effects in the Binding of Ligands to Hemoglobin

The effect of hydrogen ion, chloride, and 2,3-diphosphoglycerate upon the oxygen binding of hemoglobin may be satisfactorily described by an allosteric model employing three affinity states. The allosteric two-state model does not provide even an approximate description except under defined extreme...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Minton, Allen P., Imai, Kiyohiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1974
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC388240/
https://ncbi.nlm.nih.gov/pubmed/4364537
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