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Analytical expressions for the homotropic binding of ligand to protein dimers and trimers

Cooperative binding of a ligand to multiple subsites on a protein is a common theme among enzymes and receptors. The analysis of cooperative binding data (either positive or negative) often relies on the assumption that free ligand concentration, L, can be approximated by the total ligand concentrat...

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Main Authors: Lefurgy, Scott T., Leyh, Thomas S.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417323/
https://ncbi.nlm.nih.gov/pubmed/22230282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.12.016
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