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Analytical expressions for the homotropic binding of ligand to protein dimers and trimers

Cooperative binding of a ligand to multiple subsites on a protein is a common theme among enzymes and receptors. The analysis of cooperative binding data (either positive or negative) often relies on the assumption that free ligand concentration, L, can be approximated by the total ligand concentrat...

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Detalhes bibliográficos
Main Authors: Lefurgy, Scott T., Leyh, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417323/
https://ncbi.nlm.nih.gov/pubmed/22230282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2011.12.016
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