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Dimeric and trimeric derivatives of the azinomycin B chromophore show enhanced DNA binding
To explore the utility of the azinomycin B chromophore as a platform for the development of major-groove binding small molecules, we have prepared a series of 3-methoxy-5-methylnaphthalene derivatives containing diamine, triamine, and carbohydrate linker moieties. All bis- and tris-azinomycin deriva...
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| Publicat a: | Org Biomol Chem |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5513485/ https://ncbi.nlm.nih.gov/pubmed/28513737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7ob00944e |
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