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The Three-State Model: A Minimal Allosteric Description of Homotropic and Heterotropic Effects in the Binding of Ligands to Hemoglobin
The effect of hydrogen ion, chloride, and 2,3-diphosphoglycerate upon the oxygen binding of hemoglobin may be satisfactorily described by an allosteric model employing three affinity states. The allosteric two-state model does not provide even an approximate description except under defined extreme...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC388240/ https://ncbi.nlm.nih.gov/pubmed/4364537 |
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