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Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics
Hydroxyurea is currently the only FDA-approved drug that ameliorates the pathophysiology of sickle cell anemia. Unfortunately, substantial interpatient variability in the pharmacokinetics (PK) of hydroxyurea may result in variation of the drug's efficacy. However, little is known about mechanis...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3882360/ https://ncbi.nlm.nih.gov/pubmed/23986199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00232.2013 |
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