Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

PURPOSE: Methotrexate plasma concentration is related to its clinical effects. Our aim was to identify the genetic basis of interindividual variability in methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia (ALL). PATIENTS AND METHODS: We performed a genome-wi...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Treviño, Lisa R., Shimasaki, Noriko, Yang, Wenjian, Panetta, John C., Cheng, Cheng, Pei, Deqing, Chan, Diana, Sparreboom, Alex, Giacomini, Kathleen M., Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2009
Konular:
Original Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793040/
https://ncbi.nlm.nih.gov/pubmed/19901119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.4156
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller