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Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters
OBJECTIVE: Hydroxyurea has proven laboratory and clinical therapeutic benefits for sickle cell anemia (SCA) and other diseases, yet many questions remain regarding its in vivo pharmacokinetic and pharmacodynamic profiles. Previous reports suggest that hydroxyurea passively diffuses across cells, but...
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| Veröffentlicht in: | Exp Hematol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739778/ https://ncbi.nlm.nih.gov/pubmed/21256917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.01.004 |
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