Gene Expression Signatures of cAMP/Protein Kinase A (PKA)-promoted, Mitochondrial-dependent Apoptosis: COMPARATIVE ANALYSIS OF WILD-TYPE AND cAMP-DEATHLESS S49 LYMPHOMA CELLS

The second messenger cAMP acts via protein kinase A (PKA) to induce apoptosis by mechanisms that are poorly understood. Here, we assessed a role for mitochondria and analyzed gene expression in cAMP/PKA-promoted apoptosis by comparing wild-type (WT) S49 lymphoma cells and the S49 variant, D(−) (cAMP...

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Bibliographic Details
Main Authors: Zhang, Lingzhi, Zambon, Alexander C., Vranizan, Karen, Pothula, Kanishka, Conklin, Bruce R., Insel, Paul A.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882191/
https://ncbi.nlm.nih.gov/pubmed/18048352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708673200
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