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Virally-expressed connexin26 restores gap junction function in the cochlea of conditional Gjb2 knockout mice

Mutations in GJB2, which codes for the gap junction protein connexin26, are the most common causes of human nonsyndromic hereditary deafness. We inoculated modified adeno-associated viral vectors into the scala media of early postnatal conditional Gjb2 knockout mice to drive exogenous connexin26 exp...

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Detalhes bibliográficos
Main Authors: Yu, Qing, Wang, Yunfeng, Chang, Qing, Wang, Jianjun, Gong, Shushen, Li, Huawei, Lin, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881370/
https://ncbi.nlm.nih.gov/pubmed/24225640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.59
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