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A retro-inverso TAT-like peptide designed to deliver cysteamine to cells
A retro-inverso, TAT-like peptide wherein lysine residues are replaced with cysteine residues bearing a disulfide-linked cysteamine group is found to engage in thiol–disulfide exchange with cysteine. These peptides are transported into cells and localize to lysosomes. Cellular uptake is enhanced in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881279/ https://ncbi.nlm.nih.gov/pubmed/20843689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.07.046 |
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