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TAT-mediated photochemical internalization results in cell killing by causing the release of calcium into the cytosol of cells

BACKGROUND: Lysis of endocytic organelles is a necessary step in many cellular delivery methodologies. This is achieved efficiently in the photochemical internalization approach but the cell death that accompanies this process remains a problem. METHODS: We investigate the mechanisms of cell death t...

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Detalhes bibliográficos
Main Authors: Muthukrishnan, Nandhini, Johnson, Gregory A., Lim, Jongdoo, Simanek, Eric E., Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432654/
https://ncbi.nlm.nih.gov/pubmed/22771830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2012.06.020
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