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STING Recognition of Cytoplasmic DNA Instigates Cellular Defense
How the cell recognizes cytosolic DNA including DNA based microbes to trigger host defense related gene activation remains to be fully resolved. Here, we demonstrate that STING (for Stimulator of Interferon Genes), an endoplasmic reticulum (ER) translocon associated transmembrane protein, acts to de...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3881179/ https://ncbi.nlm.nih.gov/pubmed/23478444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.01.039 |
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