Adeno-associated virus serotypes 9 and rh10 mediate strong neuronal transduction of the dog brain

Canine models have many advantages for evaluating therapy of human central nervous system (CNS) diseases. In contrast to nonhuman primate models, naturally occurring canine CNS diseases are common. In contrast to murine models, the dog's lifespan is long, its brain is large and the diseases aff...

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Autors principals: Swain, G P, Prociuk, M, Bagel, J H, O'Donnell, P, Berger, K, Drobatz, K, Gurda, B L, Haskins, M E, Sands, M S, Vite, C H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881028/
https://ncbi.nlm.nih.gov/pubmed/24131981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2013.54
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